CJC 1295 info in plain English

Posted on September 14, 2012


CJC 1295 is a research peptide composed of a long amino acid chain which functions as a growth hormone releasing hormone (GHRH) when injected. It is important to note that CJC 1295 is a research product and currently NOT approved for use but some studies have been very promising.

For instance a study of men between the age of 53-68 years old showed improvement in lean body mass, muscle gain and strength over a three month testing period. The men were administered high doses of CJC 1295 three times per day during this time. None of the participants were asked to change their normal routines. Specifically the men taking the high doses of cjc 1295 over the three months saw gains of 7+ kg (15.4 pounds) of muscle during this time and no health issues were reported.

cjc1295 study results

The problem is with the dosing, the study participants were administered 4mg of cjc 1295 daily divided into three injections. This is equivalent to two 2000mcg vials of the peptide each day! The reason for such high and frequent doses is due to the half-life of the peptide. CJC 1295 has a half-life of just 10 minutes or less when administered and it is most effective when taken during a normal “growth hormone pulse”.

The human body does not release growth hormone continuously throughout the day it happens during certain times of the day which is known as a pulse. These pulses occur typically after strenuous physical exertion (like a workout) in the morning before eating and again in the evening before bed. Eating has a negative effect on growth hormone pulses due to the insulin level rising and suppressing the growth hormone pulse.

This can be problematic because if the peptide is not taken during a natural pulse the GH release effect will not be as great as when taken during a GH pulse.

There are a few solutions to this however. The first is through a peptide known as CJC 1295 DAC, DAC stands for Drug Affinity Complex and is designed to increase the half-life of the cjc peptide to up to EIGHT days. What this means is that every time the body experience a GH pulse there is an increase in natural growth hormone release over the course of several days. It has been found that a single dose of cjc 1295 dac can increase GH levels 2-10 times up to 6 days later!

Another solution that has been discovered is the use of a growth hormone releasing peptide (GHRP) like GHRP-2, GHRP-6 or Ipamorelin in conjunction with plain cjc-1295. The reason for this is that these GHRP’s create a GH pulse which means that the CJC-1295 will be able to work effectively. This is typically done multiple times per day for several weeks and is credited for improved muscle building and fat loss properties due to infrequent “short burst” releases as opposed to sustained releases over time, although there is no proven research to support this claim.




*The article was contributed by Brady Gonzalez and does not reflect the opinions of US Peptides. Research peptides are not approved for human consumption and are for Research purpose only!

Filed Under: CJC-1295